Electrochemically activated solutions: evidence for antimicrobial efficacy and applications in healthcare environments European Journal of Clinical Microbiology and Infectious Diseases(2012) 31:641–653

Electrochemically activated solutions (ECAS) (such as hypochlorous acid) have been shown to have broad-spectrum antimicrobial activity, and have the potential to be widely adopted within the healthcare environment ....Numerous studies have found ECAS to be highly efficacious, as both a novel environmental decontaminant and a topical treatment agent (with low accompanying toxicity) This review provides an overview of the scientific evidence for the mode of action, antimicrobial spectrum and potential healthcare-related applications of ECAS, providing an insight into these novel yet seldom utilised biocides.

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Comparative Antimicrobial Activities of Aerosolized Sodium Hypochlorite, Chlorine Dioxide, and Electrochemically Activated Solutions Evaluated Using a Novel Standardized Assay .....Journal of Antimicrobial Agents and Chemotherapy p. 2216–2225

Under the conditions of the assay, the order of antimicrobial efficacy of biocidal aerosol treatment was as follows: ECAS(Hypochlorous Acid) > chlorine dioxide & sodium hypochlorite. (Hypochlorous acid more effective than either chlorine dioxide or sodium hypochlorite)

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Evaluation of sprayed hypochlorous acid solutions for their virucidal activity against avian influenza virus through in vitro experiments

Hypochlorous acid (HOCl) solutions were evaluated for their virucidal ability against a low pathogenic avian influenza virus (AIV), H7N1. HOCl solutions containing 50, 100 and 200 ppm chlorine (pH 6) or their sprayed solutions (harvested in dishes placed at 1 or 30 cm distance between the spray nozzle and dish) were mixed with the virus with or without organic materials (5% fetal bovine serum: FBS).

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